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Global cardiovascular and cerebrovascular health prevention background

         Heavy! Adult cardiovascular and cerebrovascular diseases begin in childhood.

   Cardiovascular and cerebrovascular disease attacks are "caught off guard and can kill you in seconds."

It was once believed that atherosclerosis is the inevitable result of human aging, but with the deepening of medical research, clinical medicine has gradually realized that atherosclerosis is a long pathological process that has gone through decades, and it begins as early as infancy. happened. The Americans discovered the earliest. Seventy years ago, American researchers conducted autopsies of young soldiers who died in the Korean War and the Vietnam War, and found that half to three-quarters of the soldiers suffered from early atherosclerotic lipid plaque lesions. 

A group of autopsy data from 1160 full-term newborns to 29 years of age showed that the aorta and coronary arteries of all ages were widely lacking in individuals with early atherosclerotic lipid plaques, and adolescents between the ages of 12 and 14 About 65% have this disease, and about 8% of older children or adolescents have early atherosclerotic plaques. Another study found that typical atherosclerotic plaques can develop in the age group of 30 to 40 years old, which is consistent with the occurrence of heart disease events in this age group clinically. 

Some researchers have found lipid spots in the aorta of fetuses born to pregnant women with hypercholesterolemia, indicating that atherosclerosis can even start as early as human fetuses. 

Generally speaking, arteriosclerosis begins to appear gradually in most people after the age of 40, and it will increase rapidly by the age of 50; men are more than women, and men and women are almost equal after menopause.

More than 30 years ago, Beijing Fuwai Hospital also conducted a study to observe atherosclerosis in people of different ages. The results also found that arteriosclerosis begins in children and then gradually progresses, with the fastest progression in young and middle-aged people. In old age, basically everyone has it. However, research reports have shown that correcting risk factors at an early stage can delay atherosclerosis and prevent serious arteriosclerosis events such as cerebral infarction and myocardial infarction. The importance of early treatment is crucial! 

Why do some people suffer from cardiovascular and cerebrovascular diseases due to arteriosclerosis, while others are fine? This is because the degree of arteriosclerosis is different, which means that the blood vessels gradually become harder and less elastic than when they were young. This is inevitable. However, not everyone will form plaques during the process of arteriosclerosis, or even if plaques form, the plaques may not be very serious; for example, the plaques are small and will not affect blood flow, so they will not cause heart disease. Cerebrovascular disease. However, once severe arteriosclerosis occurs, it can cause ischemia, lead to plaque rupture and form thrombus. There may be risks of coronary heart disease, angina pectoris, myocardial infarction, severe carotid artery stenosis, and cerebral infarction and stroke. Therefore, in order to completely avoid arteriosclerosis, everyone’s degree of arteriosclerosis is different; the risk factors that determine the risk are different. 

The most important factors causing aggravation of atherosclerosis: genetic factors, high blood pressure, diabetes, high blood fat, high uric acid; if there are these 4 points, then the progress of atherosclerosis will be fast, but if the three high or high levels are not detected in time If the four high levels are not actively controlled, atherosclerosis will accelerate and progress until it develops into cardiovascular and cerebrovascular diseases. 

Blood vessels need lifelong maintenance! The lifespan of blood vessels determines the lifespan of a person! 

With the advent of the global population aging society and the rapid development of anti-infective drugs in modern medicine, human diseases have undergone major changes. Cardiovascular and cerebrovascular system diseases and tumors have become a major threat to human life and health, especially cardiovascular and cerebrovascular diseases The high incidence rate is one of the main causes of human death.

The World Health Organization calls it: “The number one health killer”

Cardiovascular and cerebrovascular diseases are the general term for cardiovascular diseases and cerebrovascular diseases, mainly referring to coronary heart disease and stroke. According to the World Health Organization's "Global Health Estimates" (Gtobal Health Estimates) report, "non-communicable diseases" account for the largest share of global deaths Seventy-four percent of the population.

Among them, the “biggest killer” is cardiovascular and cerebrovascular diseases! At present, the death rate of the two types of diseases combined has exceeded that of tumors in the world. 

The international authoritative medical journal "The Lancet" published a paper analyzing the top ten causes of death of Chinese residents in the past 30 years.

"No. 1" turned out not to be cancer, but "stroke"!

"Stroke" is also called "stroke" and "cerebrovascular accident". Among these factors, the most common and risk factor is "hypertension". According to data, about 80% of the cases are caused by high blood pressure. Caused by hypertension, at least one out of every three adults in China suffers from hypertension, and the estimated number of patients exceeds 245 million. 

In 2019, according to WHO data, the incidence of stroke in China ranks first in the world, with a stroke occurring every 6.2 seconds.

According to 2022 data, the number of deaths from cardiovascular and cerebrovascular diseases in China still ranks first. Stroke has become the leading cause of death among Chinese residents. What's even more frightening is that stroke is not just a patent of the elderly. Among young and middle-aged people aged 15-49 in China, stroke is also one of the main causes of death. 

In 2023, some scholars from Fudan University in Shanghai believed that national action is needed to deal with "stroke".

Cerebral stroke is a group of diseases that cause brain tissue damage due to sudden rupture of blood vessels in the brain or blockage of blood vessels that prevent blood from flowing into the brain, including ischemic stroke and hemorrhagic stroke (the incidence of ischemic stroke is higher, accounting for Stroke accounts for 60% to 70% of the total number of strokes. The morbidity rate is high, the mortality rate is high, and the disability rate is high. In China, the disability rate is as high as about 70%. The loss of independent living ability brings a huge burden to families and individuals. 

On June 23, 2022, the "China Cardiovascular Health and Disease Report 2021" was released in Beijing. According to the report, in China, 2 people die from cardiovascular disease (heart disease) in every death due to disease, and on average, 1 person dies from heart disease every 8 seconds. It is estimated that the number of patients with cardiovascular disease is about 330 million.

According to data from the International Diabetes Federation (IDF), the number of adults with diabetes worldwide will reach 537 million in 2021. It is expected that the prevalence of diabetes will further rise to 12.2% by 2025, and the number of patients will increase to 783 million. Diabetes costs nearly $1 trillion in health care costs worldwide.

According to the 2021 diabetes map of the International Diabetes Federation IDF, it shows that China is facing a severe situation of diabetes prevention and control. China is the country with the most adult diabetic patients. In the past 10 years (2011-2021), the number of diabetic patients in China has increased from 90 million to 140 million, an increase of 56%, of which about 72.83 million patients have not been diagnosed , the proportion is as high as 51.7%. In addition, about 170 million adults have impaired glucose tolerance, and about 27 million adults have impaired fasting blood sugar. These people are the "reserve army" of diabetic people. It is predicted that by 2045, the number of diabetic patients in China will reach 174.4 million cases.

Hyperuricemia and gout are systemic diseases that affect multiple systems. In China, gout has become the second largest metabolic disease after diabetes. Patients aged 18-35 accounted for nearly 60%. Young people became the main force of hyperuricemia and gout. Severe hyperuricemia and gout can lead to chronic kidney disease, hypertension, diabetes and cardiovascular and cerebrovascular diseases. Data show that the number of hyperuricemia and gout patients in China will be about 180 million in 2022, and it is expected to continue to grow to 200 million by 2024.

Authoritative survey data from the National Center for Cardiovascular Diseases of China shows that more and more Chinese adults have dyslipidemia, and more than 40% of them have dyslipidemia, roughly estimated to be as many as 400 million people. 

The study found that China has the highest incidence of stroke in the world, and the risk of stroke among Chinese men is the highest among men in the world.

According to the China National Center for Cardiovascular Diseases, the April 2023 report shows that cardiovascular and cerebrovascular diseases and mortality in China are still on the rise, and the number of patients with cardiovascular and cerebrovascular diseases is about 560 million.

As the population ages, it is the main driver of the continued increase in deaths from cardiovascular and cerebrovascular diseases. The burden of premature death from cardiovascular and cerebrovascular diseases is still heavy in China.

    On average, one person dies of a heart attack every 24 minutes in Taiwan.

According to statistics in 2022, there will be an increase of 30,000 to 50,000 stroke patients in Taiwan every year. In the past, 1 in every 6 people had a stroke, but now it is 1 in every 4 people. The incidence rate is increasing year by year. Patients tend to be younger 31-50, and the rate of seeking medical treatment is increasing year by year, and the rate of seeking medical treatment after the age of 50 grows exponentially. The risk factors point to the "three highs". The first is essential hypertension, the second is hyperlipidemia, and the third is type 2 diabetes. "Three highs" also lead to cardiovascular disease. In Taiwan, one person dies of stroke every 44 minutes, and the incidence rate is very high.

Cardiovascular and cerebrovascular diseases remain one of the leading causes of death in the United States. According to data in 2019, one out of every 19 deaths in the United States died of a stroke, and approximately one person died of a stroke or myocardial infarction every 40 seconds. Hypertension: 1 in 3 adults in the United States has high blood pressure, and it is estimated that nearly half of adults in the United States have high blood pressure.   

According to a report from the U.S. Congress to the U.S. Department of Health and Human Services (HHS) on January 5, 2021: Diabetes is a major public health problem in the United States. The number of people suffering from the disease is exploding, and a more comprehensive approach must be taken to prevent more people from suffering from the disease. Type 2 diabetes is the most common type. Approximately 37 million Americans, or 11% of the population, have diabetes, and if current trends continue, one in three Americans will develop this chronic disease in their lifetime. More than one in five people with diabetes do not know they have early-stage diabetes.

The prevalence of hyperlipidemia in the United States has reached 45.6%, and more than one-third of adults suffer from hyperlipidemia, with approximately 31 million people suffering from it.

There are 8,410 people who are on the verge of getting sick but don’t know about it. 

     The prevalence of gout in the United States is approximately 3.9%, and the number of new patients will reach 16-28 million in 2023. 

Data Display! On average, 1 person in Canada dies of a heart attack every 7 minutes.

       On average, one person dies of a stroke every 10 minutes.

Although Canada has perfect food safety regulations, excellent air quality, and policy protection and living environment, none of them can guarantee everyone's health perfectly. According to the 2018 State of Public Health in Canada report, major chronic diseases including cancer, cardiovascular and cerebrovascular diseases, neurological diseases, chronic respiratory diseases and diabetes remain the leading causes of death in Canada. 

     One in five adults in Canada suffers from hypertension, and it is estimated that more than 90% of Canadians who live an average life expectancy will suffer from hypertension. Young people have an increased risk of stroke. About 50,000 people in Canada have a stroke every year. On average, there is one stroke every 10 minutes, and one person dies of heart disease every seven minutes.

According to the 2018 statistics of the Canadian Diabetes Association, nearly 11.5 million Canadians have diabetes; now there should be more than 11.5 million people with diabetes or pre-diabetes.

The study found that a study titled "Diabetes in the young: A population-based study of south Asian, Chinese, and white people" in Canada was based on South Asian, Chinese, and white people. The study found that 62% of white patients with diabetes under the age of 30 had type 2 diabetes, 86% of South Asian patients had type 2 diabetes, and 87% of Chinese patients had type 2 diabetes.

The main symptoms of diabetes are lack of energy, easy thirst, frequent urination, male sexual dysfunction, impotence or difficulty maintaining an erection, blurred vision, difficulty in wound healing, and paralysis of the limbs. In severe cases, the most common complications of diabetes such as amputation due to arteriosclerosis and blockage, blindness, renal failure, uremia, cerebrovascular disease, and heart disease are all major factors leading to death. 

However, although modern medicine applies different therapeutic interventions in clinical practice, it is still unable to cure the root causes of chronic diseases such as hypertension, hyperlipidemia, diabetes, and gout. It is necessary to take medicine for life, because of the course of taking medicine for life, and various side effects are also very large. How to reduce or control the occurrence of cardiovascular and cerebrovascular complications still fails to achieve satisfactory results. 

Danny Lee, a clinical expert in cardiovascular and cerebrovascular biotechnology at Pyramid Canada, pursues his roots, pursues refinement, depth, and refinement, learns from the past, innovates with the old, learns both Chinese and Western medicine, integrates traditional medicine and modern medicine, and brings together the strengths of others to widely Open up ideas, boldly innovate, overcome difficulties, explore and find glimmers of light, hoping to benefit the health of more people around the world.